Permeability of Human Erythrocyte
نویسندگان
چکیده
The present experiments have been undertaken to measure the permeability of the human erythrocyte to sodium and potassium; to determine the temperature coefficient of these two permeabilities; and to investigate the relationship between external concentration of sodium and potassium and their relative permeabilities. In addition, thermodynamic constants of these two processes have been measured where possible. I t is in all cases desirable to make experimental observations when the cell is in a steady state, so t ha t the system remains as independent as possible of the disturbance caused by the observation. The radioactive isotopes of sodium and potassium, Na ~4 and K s, are admirably adapted for studies of this nature, as has been previously pointed out by Raker, Taylor, Weller, and Hastings (1) and Sheppard, Martin, and Beyl (2-4) in their studies on the permeability of the human erythrocyte to these elements.
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